According to Dr. Heinrich Kremer of the Cell Symbiosis Therapy Academy,
‘Histamine dilates the small blood vessels to make them permeable to larger immune cells. It also causes fluid to move from blood vessels into the tissues. This leads to swelling and pressure on nerves of the affected tissues, which can lead to migraines, painful tension in the throat, neck, spine, thigh and adductor muscles.
Acute inflammation can also cause temporary arthralgia and neuralgia (rheumatism, sciatica, lumbago, trigeminal neuralgia).’
Dr. Kremer’s original interesting article about the histamine – sciatica connection is, unfortunately, no longer online.